Oxidative Posttranslational Modifications Develop LONP1 Dysfunction in Pressure Overload Heart Failure Hoshino et al: Mitochondrial Protease Compromise in Heart Failure
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منابع مشابه
Oxidative post-translational modifications develop LONP1 dysfunction in pressure overload heart failure.
BACKGROUND Mitochondrial compromise is a fundamental contributor to heart failure. Recent studies have revealed that several surveillance systems maintain mitochondrial integrity. The present study evaluated the role of mitochondrial AAA+ protease in a mouse model of pressure overload heart failure. METHODS AND RESULTS The fluorescein isothiocyanate casein assay and immunoblotting for endogen...
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